A study on antimicrobial activity of Acalypha indica crude extraction of methanolic compound

Dried leaves of Acalypha indica was extracted with methanol by cold percolation. From the observed data, crude extraction concentration 500 and 250 μg completely arrest the bacterial growth except Enterococcus faecalis and Shigella boydii. 125 μg concentration crude extract also completely inhibit the bacterial cell growth in Escherichia coli, Pseudomonas aeruginosa, and P. mirabilis and Staphylococcus aureus. In Vibrio cholera 62.5 and 32.25 μg concentration of the crude extraction also shows inhibitory activity. The concentration which is completely arrest the bacterial growth, that is determined as minimum bactericidal (500, 250, 125, 62.5, and 31.25 μg concentration) concentration and which concentration is inhibit the bacterial growth comparing with the control culture that is determined as minimum inhibitory concentration (62.5 and 31.25 μg concentrations). From the above investigation the experimental plant may solve the multidrug resistant bacteria problem and further higher studies is need for qualitative study for the present investigation.